The following explains the genetic diseases (the basic ones that can cause bigger health problems) that our dogs have been tested on, and links to websites where you can find more information about a specific inherited disease:
EIC - a collapse due to overload characterized by muscle weakness, fever, and uncoordinated movement. The collapse usually occurs 15 minutes after strenuous physical activity (most dogs tolerate moderate activities such as walking or swimming), lasts up to 10 minutes, and is more common in temperamental animals, which are more upset when overloaded. After 30 minutes, the dog usually fully recovers, but in some cases, death can occur.
For more information: https://www.eurovetgene.com/excersise-induced-collapse-eic
PRA / PRCD - Progressive retinal atrophy is an inherited disease that occurs in many breeds, in different forms, and in different age groups (most often in early adolescence or early adulthood). It is a genetic disease whose first stage is rod cell damage and night blindness. This is followed by damage to the cone cells and complete blindness in optimal light conditions (day).
For more information: https://www.eurovetgene.com/progressive-retinal-atrophy-pra-prcd
HNPK - Hereditary nasal parakeratosis that causes dryness of the nose leading to inflammation and irritation of the skin on the nose. Clinical signs include a dry, rough nose surface that eventually shows the change in skin color from darker to lighter and diseased dogs begin to show these signs from 6 to 12 months of age.
For more information: https://vgl.ucdavis.edu/test/hereditary-nasal-parakeratosis
CNM - Centronuclear myopathy is a disease characterized by damaged muscle fibers and usually occurs after 3 or 4 months of age. The clinical picture includes hypotonia, muscle weakness, abnormal posture, stiffness of the back of the body, and difficult endurance of physical exertion (after which the symptoms are most obvious). Also, atrophy of skeletal muscles, especially head muscles, and the absence of ligament reflexes are visible.
For more information: https://www.eurovetgene.com/centronuclear-myopathy-cnm
SD2 - Skeletal dysplasia 2 is an inherited form of mild and disproportionate dwarfism, occurring primarily in Labrador working lines. The disease has a mild phenotype with short legs and affects only the length of the legs, but does not cause any vision or hearing problems, as is the case with some other similar diseases.
For more information: https://www.eurovetgene.com/skeletal-dysplasia-2-sd2-dwarfism
Narcolepsy is an inherited disease and an autonomic recessive trait for which sleep disorders are typical. Drowsiness during the day, cataplexy, and unusually fast transition from wakefulness to REM (rapid eye movement) are characteristic. Narcoleptic dogs often have sudden episodes of muscle weakness (possibility of a loss of muscle tone) associated with loss of coordination of the hind limbs and collapse. Signs usually appear between 4 weeks and 6 months of age, and the frequency of attacks varies from individual to individual.
For more information: https://www.eurovetgene.com/narcolepsy-labrador-retriever
RD / OSD - an autonomic, recessive and, inherited disease that can be noticed even before the puppy is two months old. Affected dogs are characterized by skeletal abnormalities (such as short limbs) and eye defects (vitreous dysplasia, retinal detachment, cataracts) that can cause blindness.
For more information: https://www.eurovetgene.com/retinal-dysplasia-oculoskeletal-dysplasia-rdosd
Obesity - is a serious health problem affecting dogs. It is associated with a shorter lifespan, higher incidence of pancreatitis, respiratory, urinary, reproductive, and orthopaedic disorders. An association with a higher incidence of certain cancers was also observed.
For more information: https://www.eurovetgene.com/obesity
The table shows the possibilities of inheriting the genetics of puppies passed to them by their parents tested for a specific genetic disease.
Also, all of our males have DNA profiles made, and some of our dogs have been tested for the pigments they transmit.
Locus D - the pigment responsible for diluting the dye. The MLPH gene encodes the protein melanophilin, a key component in the production of hair and skin pigment. Mutations in this gene can cause various forms of color thinning. In black dogs, the mutation can cause blue or gray hair, and in chocolate dogs, light brown or isabella. Also, the MLPH gene can be the cause of diluted pigment in the nose, paws, and eyes.
For more information: https://www.eurovetgene.com/d-locus
Locus B - by testing the TYRP1 gene, it is possible to know if a Labrador transmits chocolate color.
For more information: https://www.eurovetgene.com/b-locus-2
Locus E - by testing the MC1R gene, it is possible to know if a Labrador transmits yellow color.
For more information: https://www.eurovetgene.com/e-locus
All rights for all of the photos and information contained within this web page are reserved.
Noa Land kennel
Noa Land kennel